Table 2.
Location | Selectins | Selectin Ligands | Chemokine Receptors and Ligands | Integrins | Integrin Ligands |
---|---|---|---|---|---|
Peripheral lymph nodes | L-selectin [82] | PNAd [83] | CCR7, CCL19, CCL21 [57,84,85] | LFA-1 [86] | ICAM-1, ICAM-2 [86,87] |
Mesenteric lymph node | L-selectin [82] | MAdCAM-1, PNAd [83,88] |
CCR7, CCL19, CCL21 [89] | α4β7, LFA-1 [90,91] | MAdCAM-1 [90] |
Peyer’s patches in gut mucosa | P-selectin 1, L-selectin [92] |
PSGL-1, MAdCAM-1 [93] |
CCR7, CCL21 [94] | α4β7, LFA-1 [91,95] | MAdCAM-1 [95] |
Lungs in IAV infection 1 | L-selectin [2] | Not known | CXCR1, CXCR3, CCR4, CCR5, CXCR6 [96] | VLA-4, LFA-1 [96] | VCAM-1, ICAM-1 [96] |
1 Required during inflammation/infection.