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. 2022 Feb 18;10(2):91. doi: 10.3390/toxics10020091

Figure 3.

Figure 3

Evaluation of hepatotoxicity of PFAS by measuring the enzyme activity of ALT and GDH biochemical markers on mouse liver organoids treated for 1 and 3 h with 1 mM, 500 µM and 100 µM. (A) ALT activity increased starting from the lowest concentration (100 µM) for both long and short PFASs. (B) GDH activity followed the same trend showing an increase from the lowest concentration of treatment. p-value was calculated vs. (NT) untreated samples (* indicates p-value < 0.01).