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. 2022 Jan 21;58(2):165. doi: 10.3390/medicina58020165

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Multimodal imaging signs in APMPPE. Fundus (top left) shows numerous bilateral placoid discolored lesions, corresponding to ICGA hypofluorescent choriocapillary non-perfusion lesions (top right two frames). SD-OCT pictures show alteration and thickening of outer retina (ONL/photoreceptor IS/OS layer middle left picture, crimson arrow) and loss of photoreceptor IS/OS line (bottom left picture, between the two yellow arrows). BL-FAF shows hyperautofluorescence, indicating loss of photoreceptor outer segments as explained in paragraph 2.1 (bottom middle picture) OCT-A (bottom right picture) shows choriocapillary drop-out (dark areas).