Table 2.
MEWDS (Figure 1) | APMPPE (Figure 2) | MFC (Figure 3) | SC (Figure 4) | |
---|---|---|---|---|
ICGA | Intermediate-late hypofluorescence | Early to late hypofluorescence | Early to late hypofluorescence (scars and new lesions) | Hypofluorescence with perilesional hyperfluorescence |
BL-FAF | Hyperautofluorescence of acute lesions | Hyperautofluorescence in active lesions/hypofluorescence of severe acute and atrophic lesions | Hyperautofluorescence (active lesions) Hypoautofluorescence (atrophic lesions/scars) |
Active: Hypoautofluorescence surrounded by hyperautofluorescent halo Semi-Active: linear hypoautofluorescence around hyperautofluorescent lesion Inactive: Hypoautofluorescence |
SD-OCT | Loss of photoreceptor OS Interruption and/or damage to IS/OS line |
Thickening and denaturation of outer retina (hyperreflective area occupying the outer retina) | Loss of photoreceptors OS/Interruption and/or damage to IS/OS line atrophic lesions/ICNV | Hyperreflective accumulations in the outer retina/ICNV |
OCT-A | Absent or subtle signs of choriocapillaris drop-out | Patchy choriocapillaris drop-out | Patchy Choriocapillaris drop-out/ICNV | Geographic areas of choriocapillaris drop-out/ICNVs |
FA | Subtle early to late hyperfluorescence | Early hypofluorescence/late hyperfluorescence (staining and pooling) in severe non-perfusion | Early hypofluorescence/late hyperfluorescence of scared-atrophic lesions No FA signs of new lesions |
Scars/atrophy: early hypofluorescence and late hyperfluorescence (window defect) surrounded by late more hyperfluorescent rim, if lesions are progressing |
BL-FAF = blue light fundus autofluorescence. ICGA = indocyanine green angiography. SD-OCT = spectral domain optical coherence tomography. OCT-A = OCT angiography FA = fluorescein angiography. ICNVs = inflammatory choroidal neovessels IS/OS = inner/outer segment line.