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. 2022 Jan 20;14(2):241. doi: 10.3390/pharmaceutics14020241

Table 6.

EGFR-targeted PDT performed with EGFR ligands as targeting agents and conjugated with carrier molecules.

Targeting Agent PS Cargo In Vitro Studies In Vivo Studies Ref.
Erlotinib Heptamethine cyanine dye (Cy7) Chitosan nanoparticles A549, PC-9, H1975 A549, PC-9, or H1975 cells in female Balb/c-nude mice [130]
Erlotinib Indocyanine green (ICG) Chitosan nanoparticles PC9 [131]
Erlotinib Indocyanine green (ICG) Mesoporous silica nanoparticles (MSN) A549, PC-9, and H1975 A549, PC-9, or H1975 cells in Balb/c nude mice [132]