Skip to main content
. 2022 Jan 20;14(2):241. doi: 10.3390/pharmaceutics14020241

Table 9.

EGFR-targeted PDT performed with anti-EGFR scFV.

Targeting Agent PS In Vitro Studies In Vivo/Ex Vivo Studies Ref.
scFv-425 Chlorin e6 (Ce6) A431, MDA- MB468, MDA-MB-231, SiHa, CHO-K1 [195]
scFv-425 IR700DX MDA-MB-468, MDA-MB-453, MDA-MB-231, Hs758T, MCF-7 Human breast cancer biopsies and normal
breast tissues
[196]
scFv-425 IR700DX A431, HEK-293T, A2058 [197]
scFv-425 IR700DX OVCAR-3, SKOV-3,
IGROV-1, A2780
Human ovarian cancer biopsies and ascite samples [198]