Table 10.
EGFR-targeted PDT performed with anti-EGFR nanobodies.
| Targeting Agent | PS | In Vitro Studies | In Vivo Studies | Ref. |
|---|---|---|---|---|
| 7D12, 7D12-9G8 | IRDye700DX | 3T3 2.2, 14C, A431, HeLa | [211] | |
| 7D12, 7D12-9G8 | IRDye700DX | OSC- 19-luc2-cGFP, HeLa, SW620 |
OSC-19-luc2-cGFP cells in nude Balb/c female mice | [212] |
| 7D12 | IRDye700DX | A431, E98, SKOV-3 | Clinical ascites samples | [213] |
| 7D12, 7D12-9G8 | IRDye700DX | A431, HeLa, HEK293T, UM-SCC-14C | Patient-Derived Head and Neck Cancer Organoids | [167] |
| 7C12 | RuII Polypyridyl | A431, MDA-MB 435S | [214] | |
| 7D12, 7D12-9G8 | RDye700DX | OSC-19-luc2-cGFP | OSC-19-luc2-cGFP cells in female BALB/c nude mice | [215] |
| 7D12, 7D12-9G8 | IRDye700DX | A431, scc-U8 | [216] | |
| 7D12 | IRDye700DX | MS1, OSC | [217] | |
| NBA | IRDye700DX | SCCF1, SCCF2, SCCF3, HeLa, MCF7 | [218] | |
| 7D12 | IRDye700DX | A431 | Mice bearing A431 xenografts. | [219] |
| 7D12 | Benzophenothiazine | A431, 4T1, MCF-7, HeLa | 4T1cells in female Balb/c mice |
[220] |