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. 2022 Jan 20;14(2):241. doi: 10.3390/pharmaceutics14020241

Table 13.

EGFR-targeted PDT performed with anti-EGFR affibodies conjugated with carrier molecules.

Targeting Agent PS Cargo In Vitro Studies In Vivo Studies Ref.
Anti-EGFR Affibody TiO2 Core–shell nanoparticle—titanium dioxide (TiO2) on a NaYF4:Yb, Tm UCN core OSCC, A431, MCF-7, OSCC cells in 6–8 week female Balb/c nude mice [230]
Anti-EGFR Affibody Pheophorbide A (PhA) Poly[(2-(pyridin-2-yldisulfanyl)ethyl acrylate)-co-[poly(ethylene glycol)]] (PDA-PEG) nanogel UMSCC 22A UMSCC 22A cells in female Balb/c nude mice (8–10 week old) [231]