Table 1.
Baseline characteristics of the study population.
| All (n = 210) | NA | ||
|---|---|---|---|
| Sociodemographics | |||
| Age, years, mean (SD) | 60.7 (14.0) | 0 | |
| Male, (n (%)) | 143 (68.1) | 0 | |
| Married, (n (%)) | 109 (51.9) | 2 | |
| Educational status “< High school”, (n (%)) | 72 (34.3) | 0 | |
| Care measures | |||
| Recent surgical history, (n (%)) | 2 | ||
| Emergency | 76 (36.5) | ||
| Elective surgery | 47 (22.6) | ||
| No history | 47 (22.6) | ||
| ICU length of stay days: median, mean (SD) (Q1;Q3) |
24, 31.9 (27.2) (13; 43.2) |
16 | |
| Mechanical ventilation, (n (%)) | 177 (84.7) | 1 | |
| if applicable, days: median, mean (SD) (Q1;Q3) |
8, 14.6 (18.92) (2; 21.5) |
9 | |
| Renal replacement therapy, (n (%)) | 61 (29.3) | 2 | |
| if applicable, days: median, mean (SD) (Q1;Q3) |
0, 3.26 (8.5) (0; 2) |
7 | |
| Clinical Measures | |||
| Source of infection, (n (%)) | 6 | ||
| Community acquired | 77 (36.7) | ||
| Nosocomial (ICU or IMC) | 106 (52.0) | ||
| Nosocomial (general ward or nursing home) | 21 (10.3) | ||
| Site of infection (n (%)) # | 3 | ||
| Pneumonia | 89 (43) | ||
| intraabdominal | 32 (15.5) | ||
| respiratory tract, other | 25 (12) | ||
| urogenital | 20 (9.7) | ||
| bone, soft tissue | 19 (9.2) | ||
| cardiovascular | 13 (6.3) | ||
| Comorbidity: Charlson Index a,*, mean (SD) | 3.83 (3.0) | 1 | |
| ICD-diagnoses, No., median, mean (SD) | 9, 9.5 (5.1) | 0 | |
| BMI, mean (SD) | 27.5 (5.9) | 6 | |
| Depression, MDI b,*, mean (SD) | 17.7 (9.9) | 1 | |
| PTSD, PTSS-10 c,*, mean(SD) | 23.1 (9.8) | 1 | |
| Cognition: TICS-M b,f,†, mean (SD) | 33.7 (3.4) | 0 | |
| Neuropathic symptoms: NSS d,* mean (SD) | 3.6 (3.2) | 4 | |
| Score 3–10, (n (%)) | 123 (58.6) | ||
| Pain | |||
| Intensity: GCPS PI e,* mean (SD) | 43.3 (24.8) | 3 | |
| Disability: GCPS DS e,* mean (SD) | 36.3 (34.6) | 5 | |
| Quality-of-Life measures | |||
| SF-36 MCS e,†, mean (SD) | 49.0 (12.7) | 4 | |
| SF-36 PCS e,†, mean (SD) | 26.0 (8.9) | 15 | |
Abbreviations: BMI, Body Mass Index; GCPS DS, Graded Chronic Pain Scale Disability Score [27]; GCPS PI, Graded Chronic Pain Scale Pain Intensity [27]; ICU, intensive care unit; IMC, Intermediate Care; MDI, Major Depression Inventory [23]; NA, Not Available; NSS, Neuropathic Symptom Score [26]; PTSD, Post Traumatic Stress Disorder; PTSS, Post-Traumatic Symptom Scale [28]; SF-36 MCS, Short Form (36) Health Survey Mental Component Score [28]; SF-36 PCS, Short Form (36) Health Survey Physical Component Score [28]; TICS-M, modified Telephone Interview for Cognitive Status [24]; i, intervention; c, control. Anchors: * high score indicates high impairment, † high score indicates low impairment. Ranges: a The range of possible scores is 0–37, b The range of possible scores is 0–50, c The range of possible scores is 10–70, d The range of possible scores is 0–10, e The range of possible scores is 0–100, f values only above 27 (inclusion criteria). # main six sites of infection are shown.