Table 2.
Comparison of the E-cfDNA sensor with other techniques for DNA detection.
| Techniques | Name | Linear Range | LOD | Refs. |
|---|---|---|---|---|
| Fluorescence Biosensors |
CRISPR-Cas12a-based cfDNA biosensing system | 1 fM to 100 pM | 0.34 fM | [8] |
| DNA tetrahedral-based fluorescent microarray platform | 100 aM to 1 pM | 10 aM | [39] | |
| Electrochemical Biosensors |
Label-free electrochemical biosensor | 0.01 fM to1 pM | 2.4 aM | [28] |
| HCR and DNA nanostructure-based electrochemical biosensor | 1 fM to 100 pM | 100 aM | [34] | |
| Electrochemiluminescence Biosensors |
DNA walk-based electrochemiluminescence biosensing | 1 fM to 100 pM | 0.18 fM | [40] |
| Cas12a-based electrochemiluminescence biosensor | 1 pM to 10 nM | 0.48 pM | [41] | |
| E-cfDNA sensor | 1 aM to 1 pM | 1 aM | This work | |