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. 2022 Feb 17;23(4):2223. doi: 10.3390/ijms23042223

Table 1.

Unique features of natural cell membranes.

Cell Type Features
Plasma membrane RBC Immunosuppressive effect, long-term blood circulation, and neutralization of toxins
Platelet Specific binding affinity to injured vasculature, pathogen adhesion, reduced cellular uptake by macrophages, and prolonged blood retention time
Macrophage Inflammation site-specific accumulation, neutralization of inflammatory cytokines, antigen-homing affinity
Cancer Homotypic targeting, and low intrinsic immunogenicity
Cell organelle membrane Mitochondria Selectively binding to mitochondrial membrane ligands, and neutralization of toxins
Nucleus Improved transfection efficiency in gene therapy