Figure 11.

Effects of simulated microgravity on collagen gel matrix contraction of human dermal fibroblasts exposed or unexposed to the RPM for 24 h. The diameter of each collagen gel was measured using ImageJ v 1.47 h software. (A) Photos show the action of human fibroblasts exposed to µG (RPM) or to 1g (OG) on collagen gel contraction. (B) Values are expressed as a fold increase of on-ground control (OG). Each column represents the mean value ± SD of three independent experiments performed in duplicate, with SD represented by vertical bars. * p < 0.05 versus OG by an unpaired two-tailed t-test.