Figure 2.

Electron microscopy image of filamentous phage (left) and electron density model (center) of filamentous phage M13 (courtesy of Lee Makowski and Gregory Kishchenko). Blue and red arrows depict the sharp and blunt ends of the phage capsid with attached minor coat proteins pIII/pIV and pVII/pIX, respectively (five copies each). Major coat protein (~2700 copies) forms the tubular capsid around viral single-stranded DNA (scale bar: 100 nm). 3D structure (right) of the complex between phage displaying the peptide EDYSELVSQ (green) with FGFR3 (red). Here, the peptide-displayed phages are designated by the structure of the inserted foreign peptides.