Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetic parameters of three myristic variants after 7 days period injection adapted from Biscan et al.
| Parameter (Units) | Monomeric Myr | Dimeric Myr | Trimeric Myr |
|---|---|---|---|
| kabs (min−1) | 0.0562 | 0.0213 | 0.0341 |
| t1/2 abs (min) | 12.3 | 32.5 | 20.3 |
| kβ (min−1) | 0.0218 | 0.0050 | 0.0015 |
| t1/2 β (min) | 54.1 | 139.0 | 465.3 |
| Tmax (min) | 60 | 120 | 120 |
| Cmax (µg/mL) | 21.4 | 6.1 | 0.9 |
| AUC (µg/mL*min) | 3768.1 | 3511.1 | 984.6 |
| MRT (min) | 644.7 | 1534.5 | 2009.6 |
