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. 2022 Feb 14;14(4):734. doi: 10.3390/polym14040734

Table 1.

Chromatographic conditions for determination of benzydamine, tolfenamic acid and betahistine. The mobile phase for BZ and BET was a mixture of Phase A and Phase B (80:20). pH was adjusted to 10.5 with triethyl amine.

Model Drug Mobile Phase UV Detection Retention Time
(min)
Phase A Phase B
Benzydamine water acetonitril 260 nm 4.01 ± 0.10
Betahistine water acetonitril 307 nm 4.04 ± 0.10
Tolfenamic acid 60% acetonytril with 0.1% formic acid 280 nm 7.39 ± 0.11