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. 2022 Jan 30;12(2):130. doi: 10.3390/metabo12020130

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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A subgroup analysis showed trended differences in steatotic liver injury depending on disease activity. In a subgroup cohort analysis comparing celiac patients with anti-tTG levels ≤ 1 and those with anti-tTG levels > 1, we could show that those patients with anti-tTG > 1 showed a trend towards increased steatosis as assessed by CAP (A) and MRI-FFS (B). Those individuals with anti-tTG levels > 1 showed a tendency of increased transaminase levels of AST (C) and ALT (D) as well as of hepatocellular apoptosis marker M30 (E) and overall cell death marker M65 (F). ns stands for not significant.