Figure 2.

Sensory impairments instigated by diiodohydroxyquinoline administration in young/adult male/female rats. Panels represent: (A) paw withdrawal latency (CAPWL) in the cold allodynia test, (B) reaction latency (HPRL) in the hot plate test, and (C) mechanical threshold (RSMT) in Randall–Selitto test. Each bar with a vertical line represents the mean ± S.D. of 10 rats per group. a vs. control young male, b vs. control young female, c vs. control adult male, d vs. control adult female, e vs. DHQ young male, and f vs. DHQ young female using three-way ANOVA followed by Tukey’s post hoc test; p < 0.05. DHQ; diiodohydroxyquinoline.