Figure 1.
Social behavioral deficits in CD157KO mice were improved by chronic L-carnosine intake. (A) Experimental scheme of the three-chamber social recognition test. The social preference test was performed after the sociability test. (B) The sociability test. The time spent around the wire cage with a social target (Stranger 1) or with an object was measured. (C) The sociability index. (D) The social preference test. The time spent around the wire cage with a familiar social target (Stranger 1) or with an unfamiliar social target (Stranger 2) was measured. (E) The social preference index. The numbers of mice used in each experiment are indicated in the graphs. Data are presented as the mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001. WT: wild-type, Str: stranger, Car, L-carnosine.
