Figure 3.

Representation of normalized parameters related to the immune cell populations with respect to their relative variations before and after stimulation with the SARS -CoV-2 Spike protein. High-responding subjects (black circles), low-responding ones (diamonds), and controls (stars). T cell populations: CD4⁺ CM (central memory, CD45RA⁻ CCR7⁺), CD4⁺ EM (effector memory, CD45RA⁻ CCR7⁻), CD4⁺ Th17 (CXCR3⁻ CCR6⁺), CD8⁺ CM (central memory, CD45RA⁻ CCR7⁺), CD8⁺ EM (effector memory, CD45RA⁻ CCR7⁻). B-cell populations: B naïve (CD19⁺ CD27⁻ IgD⁺), B transitional (CD19⁺ CD27⁻ IgD⁺ CD24^high CD38^high), B MUnsw (memory unswitched CD19⁺ CD27⁺ IgD⁺), and B MSw (memory switched CD19⁺ CD27⁺ IgD⁻).