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. 2022 Feb 20;27(4):1426. doi: 10.3390/molecules27041426

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The interaction of the 79 proteins that were enhanced in their expression in a comparable way to late and total apoptosis levels and those that are predicted to associate with anticancer drugs (e.g., doxorubicin, oxaliplatin, 5-fluorouracil, and capecitabine) or apoptotic proteins (e.g., caspase 3 and caspase 9) using the STITCH version 5.0 software. The dashed circles indicate the filtered proteins from the proteomics dataset that interact with anticancer drugs and apoptotic proteins.