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. 2022 Feb 14;27(4):1281. doi: 10.3390/molecules27041281

Table 1.

Differential KEGG pathways predicted via PICRUSt software in the Xn prevention experiment.

Number Description P_APP_PS1_vs_P_WT P_WT_5Xn_vs_P_WT P_APP_PS1_5Xn_vs_P_APP_PS1
log2
(Fold Change)		 p Value Up/Down log2
(Fold Change)		 p Value Up/Down log2
(Fold Change)		 p Value Up/Down
ko05010 Alzheimer′s disease 1.732027242 0.017025339 up 2.366161715 0.003558436 up
ko04974 Protein digestion and absorption 1.00459934 0.018638107 up
ko00830 Retinol metabolism −4.572428141 1.24 × 10−5 down −4.157153572 1.83 × 10−5 down
ko04142 Lysosome −4.227876257 2.30 × 10−5 down −3.679825761 0.000455767 down
ko00980 Metabolism of xenobiotics by cytochrome P450 −4.66899817 7.55 × 10−5 down −4.787486299 2.55 × 10−5 down
ko00363 Bisphenol degradation −4.919555706 0.000142318 down −4.808225969 0.000339327 down
ko00195 Photosynthesis −5.509890045 0.000278555 down −4.495865401 0.00477363 down
ko00642 Ethylbenzene degradation −4.243304316 0.000594088 down −4.249603903 0.000570651 down
ko00523 Polyketide sugar unit biosynthesis −5.139057953 0.000781219 down −4.199953052 0.011321054 down
ko00311 Penicillin and cephalosporin biosynthesis −1.749057294 0.002085877 down −1.299383141 0.049212447 down 1.517322773 0.012792112 up
ko00253 Tetracycline biosynthesis −4.758378649 0.004146843 down −3.783153775 0.028842448 down
ko00364 Fluorobenzoate degradation −1.537476491 0.004302729 down −1.422606062 0.010323156 down
ko00791 Atrazine degradation −1.904490251 0.006353534 down 1.85619649 0.010297892 up
ko00906 Carotenoid biosynthesis −1.136194803 0.008280216 down −1.047940043 0.046641794 down
ko05200 Pathways in cancer −1.582997558 0.010892181 down
ko00930 Caprolactam degradation −1.339589301 0.020127255 down −1.479654328 0.016294803 down
ko00903 Limonene and pinene degradation −2.82113561 0.021578285 down −4.301375008 0.000240924 down
ko00643 Styrene degradation −1.177109587 0.013561769 down
ko00622 Xylene degradation −2.887030853 0.018878669 down

Differential pathways with log2 fold change > 1. Black boldface words indicate representative KEGG pathways. PICRUSt, Phylogenetic Investigation of Communities by Reconstruction of Unobserved States.