Table 1.
Antimicrobial properties of the tested compounds.
| Entry | Compd. | MIC, μg/mL ± SE (μmol) | |||
|---|---|---|---|---|---|
| S. Aureus (ATCC 6538) | B. Subtilis (ATCC 6633) | P. Aeruginosa (ATCC 15692) | E. Coli (ATCC 47076) | ||
| 1 | 3a | 16 ± 2.1 (32.888) | 4 ± 0.3 (8.222) | 64 ± 1.4 (131.552) | 32 ± 1.0 (65.776) |
| 2 | 3b | 32 ± 1.5 (63.932) | 32 ± 2.1 (63.932) | 64 ± 1.9 (127.864) | 32 ± 2.5 (63.932) |
| 3 | 3c | 32 ± 1.1 (60.540) | 32 ± 2.7 (60.540) | 64 ± 2.9 (121.079) | 32 ± 1.6 (60.540) |
| 4 | 3d | 32 ± 1.6 (57.078) | 32 ± 2. 4 (57.078) | 64 ± 3.1(114.155) | 32 ± 2.0 (57.078) |
| 5 | 3e | 32 ± 2.2 (55.495) | 32 ± 1.9 (55.495) | 64 ± 2.1 (110.990) | 32 ± 1.0 (55.495) |
| 6 | 3f | 32 ± 1.4 (70.721) | 8 ± 0.4 (17.680) | 32 ± 1.6 (70.721) | 32 ± 2.8 (70.721) |
| 7 | 3g | 32 ± 1.5 (68.594) | 32 ± 2.4 (68.594) | 32 ± 1.2 (68.594) | 32 ± 2.7 (68.594) |
| 8 | 3h | 32 ± 1.3 (64.704) | 32 ± 0.7 (64.704) | 32 ± 0.5 (64.704) | 32 ± 1.1 (64.704) |
| 9 | 3i | 32 ± 2.1 (60.765) | 32 ± 1.4 (60.765) | 32 ± 0.8 (60.765) | 32 ± 0.5 (60.765) |
| 10 | 3j | 64 ± 2.5 (117.948) | 32 ± 1.3 (58.974) | 64 ± 1.8 (117.948) | 32 ± 0.9 (58.974) |
| 11 | 3k | 32 ± 2.1 (62.919) | 32 ± 1.3 (62.919) | 32 ± 1.3 (62.919) | 32 ± 2.1 (62.919) |
| 12 | 5a | 4 ± 0.2 (10.015) | 1 ± 0.1 (2.504) | 32 ± 0.8 (80.116) | 32 ± 1.6 (80.116) |
| 13 | 5b | 4 ± 0.1 (9.583) | 1 ± 0.1 (2.396) | 32 ± 1.2 (76.663) | 32 ± 2.4 (76.663) |
| 14 | 5c | 8 ± 0.3 (18.439) | 2 ± 0.1 (4.610) | 32 ± 1.9 (73.757 | 32 ± 0.7 (73.757) |
| 15 | 5d | 2 ± 0.1 (4.500) | 1 ± 0.1 (2.250) | 32 ± 1.6 (72.004) | 32 ± 2.2 (72.004) |
| 16 | 5e | 4 ± 0.2 (9.336) | 1 ± 0.1 (2.334) | 32 ± 2.2 (74.686) | 32 ± 1.6 (74.686) |
| 17 | 5f | 8 ± 0.2 (16.706) | 4 ± 0.3 (8.353) | 32 ± 1.4 (66.825) | 32 ± 0.6 (66.825) |
| 18 | 7a | 8 ± 0.3 (19.980) | 2 ± 0.2 (4.995) | 8 ± 0.1 (19.980) | 32 ± 0.9 (79.918) |
| 19 | 7b | 8 ± 0.2 (19.980) | 2 ± 0.1 (4.995) | 32 ± 1.2 (79.918) | 32 ± 1.0 (79.918) |
| 20 | 7c | 8 ± 0.1 (19.930) | 2 ± 0.1 (4.983) | 32 ± 1.1 (79.721) | 32 ± 0.7 (79.721) |
| 21 | 9a | 32 ± 0.4 (62.189) | 32 ± 2.0 (62.189) | 32 ± 1.3 (62.189) | 32 ± 1.6 (62.189) |
| 22 | 9b | 32 ± 1.7 (63.932) | 32 ± 1.3 (63.932) | 32 ± 2.5 (63.932) | 32 ± 3.4 (63.932) |
| 23 | 9c | 32 ± 0.9 (58.332) | 32 ± 0.5 (58.332) | 32 ± 0.8 (58.332) | 32 ± 1.0 (58.332) |
| 24 | 11a | 32 ± 2.7 (79.320) | 32 ± 1.2 (79.320) | 32 ± 2.2 (79.320) | 32 ± 2.5 (79.320) |
| 25 | 11b | 32 ± 1.2 (69.037) | 32 ± 1.4 (69.037) | 64 ± 2.8 (138.074) | 32 ± 1.1 (69.037) |
| 26 | 11c | 32 ± 0.8 (70.572) | 16 ± 0.4 (35.286) | 64 ± 1.5 (141.143) | 32 ± 0.9 (70.572) |
| 27 | 11d | 32 ± 1.0 (76.212) | 32 ± 1.2 (76.212) | 32 ± 1.7 (76.212) | 32 ± 2.1 (76.212) |
| 28 | 11e | 32 ± 0.2 (75.934) | 32 ± 1.3 (75.934) | 32 ± 0.5 (75.934) | 32 ± 0.3 (75.934) |
| 29 | 11f | 32 ± 1.7 (71.831) | 32 ± 0.3 (71.831) | 32 ± 1.9 (71.831) | 32 ± 0.8 (71.831) |
| 30 | 13 | 32 ± 1.0 (80.323) | 32 ± 0.9 (80.323) | 32 ± 1.5 (80.323) | 32 ± 0.6 (80.323) |
| 31 | 15 | 32 ± 0.4 (61.349) | 32 ± 0.2 (61.349) | 32 ± 0.3 (61.349) | 32 ± 0.7 (61.349) |
| 32 | Linezolid | 2 ± 0.1 (5.929) | 0.25 ± 0.01 (0.741) | 32 ± 0.7 (94.857) | 8 ± 0.2 (23.714) |
| 33 | Ciprofloxacin [24] | 1250.0 ± 9.6 (3772.4) | NT | 4.8 ± 0.5 (14.5) | NT |
| 34 | Norfloxacin [24] | 1250.0 ± 14.2 (3914.3) | NT | 4.8 ± 0.2 (15.0) | NT |
NT = not tested.