Table 2.
Variables with statistically significant differences among diabetic patients infected with the two species of Proteeae.
| Variable | Sample of Diabetic Patients Infected with P. mirabilis
n1 = 75 |
Sample of Diabetic Patients Infected with P. stuartii
n2 = 18 |
p Value |
|---|---|---|---|
| Number of antibiotics [median, IQR] | 2 (2) | 5 (3) | <0.001 |
| Days with CVC [median, IQR] | 2 (12) | 16.50 (20) | 0.032 |
| Days with UC [median, IQR] | 0 (10) | 19 (19) | 0.019 |
| Number of antibiotics with resistance/pathogen [median, IQR] | 1(4) | 9 (5) | <0.001 |
| Anti-biotherapy prior to ICU [n, %] | 9 (12.00) | 8 (44.44) | 0.003 |
| Mechanical ventilation [n, %] | 18 (24.00) | 13 (72.22) | <0.001 |
| Urinary catheter [n, %] | 31 (41.33) | 15 (83.33) | 0.001 |
| Tracheostomy [n, %] | 8 (10.67) | 10 (55.55) | <0.001 |
| Blood transfusions [n, %] | 17 (22.67) | 11 (61.11) | 0.001 |
| Nasogastric nutrition [n, %] | 18 (24.00) | 15 (83.33) | <0.001 |
| Mechanical ventilation 0 h [n, %] | 57 (76.00) | 5 (27.77) | <0.001 |
| Mechanical ventilation ≥ 96 h [n, %] | 16 (21.33) | 13 (72.22) | <0.001 |
| Discharge status - Deceased [n, %] | 20 (26.67) | 9 (50.00) | 0.054 |
| HCAI [n, %] | 17 (22.67) | 13 (72.22) | <0.001 |
| Blood culture [n, %] | 3 (4.00) | 6 (33.33) | 0.001 |
| Catheter tip [n, %] | 2 (2.67) | 6 (33.33) | <0.001 |
| Wound swab [n, %] | 48 (64.00) | 3 (16.67) | <0.001 |
| WT phenotype [n, %] | 24 (32.00) | 0 (0) | 0.005 |
| DTR phenotype [n, %] | 0 (0) | 7 (38.89) | <0.001 |
| MDR phenotype [n, %] | 26 (34.67) | 18 (100) | <0.001 |
| XDR phenotype [n, %] | 3 (4.00) | 11 (61.11) | <0.001 |
| Aminoglycoside resistance [n, %] | 3 (4.00) | 9 (50.00) | <0.001 |
| ESBL [n, %] | 6 (8.00) | 9 (50.00) | <0.001 |
| Carbapenem resistance [n, %] | 1 (1.33) | 12 (66.67) | <0.001 |
| Fluoroquinolone resistance [n, %] | 10 (13.33) | 17 (94.44) | <0.001 |
| Sulphonamide resistance [n, %] | 41 (54.67) | 18 (100) | <0.001 |
Legend: n, number; IQR, interval between quartiles; CVC, central venous catheter; ICU, intensive care unit; h, hour; HCAI, healthcare associated infections; WT, wild type; DTR, difficult-to-treat resistance; MDR, multi-drug resistant; XDR, eXtensive Drug Resistance; OR, odds ratio; HR, hazard ratio; p, the threshold of statistical significance; ESBL, extended spectrum beta-lactamase.