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. 2022 Feb 10;14(2):393. doi: 10.3390/pharmaceutics14020393

Table 1.

IC50 values of metallodendrons and temozolomide (TMZ).

Cell Line IC50, µM
CuD AuD TMZ
BTSC233 3.2 ± 0.3 11.5 ± 2.9 n/a 1
JHH520 4.8 ± 1.1 6.4 ± 2.0 n/a
NCH644 5.9 ± 0.8 11.3 ± 2.8 n/a
SF188 0.34 ± 0.21 12.3 ± 2.5 ~125 2
U87 (adherent) 4.7 ± 3.0 15.0 ± 3.6 n/a
U87 (suspension) 11.1 ± 3.8 14.9 ± 2.8 n/a

1 IC50 could not be determined; 2 value predicted from data fitting.