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. 2022 Feb 14;23(4):2118. doi: 10.3390/ijms23042118

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Actin-binding small molecules: (a) Phalloidin (7BTI [54]). (b) Jasplakinolide (6T23 [99]). (c) Latrunculin A, (1ESV [100], Gelsolin domain 1 is shown in green); subdomains of actin are indicated as Subd-1~4. ATP is shown in cyan. (d) Cytochalasin D (3EKS [101]). (e) Kabiramide C (1QZ5 [102]). (f) Mycalolide B (6MGO [103]). (g) Reidispongiolide A (2ASM [104]). (h) Sphinxolide (2ASO ([104]). (i) Aplyronine A (1WUA [105]). (j) Chivosazole A (6QRI [106]). (k) Swinholide (1YXQ [107]). (l) Rhizopodin (2VYP [108]). (m) Lobophorolide (3M6G [109]). Actin-binding small molecules are shown in blue. Actin shown from pointed (left) to barbed (right) end with red.