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Cleavage and recombination with paired nonidentical sites. The DNA substrates carried two sites for QQR (QQ), two sites for QNK (KK), or one each for QQR and QNK (QK). They were injected into oocytes followed by no enzyme (−), with a single enzyme (Q or K), or with a mixture of the two enzymes (QK). In each case, 0.3 fmol of DNA and 15 fmol of each enzyme were injected.
