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. 2022 Feb 2;14(2):351. doi: 10.3390/pharmaceutics14020351

Table 1.

Cytotoxicity of bark essential oil and active fractions against Hep G2 cells.

Specimen Concentration
(μg/mL)
Cytotoxicity *
(%)
IC50 *
(μg/mL)
Bark oil 12.5 10.23 ± 0.98 54.31 ± 0.60 a
25 22.20 ± 0.10
50 49.47 ± 0.17
100 77.80 ± 0.17
S2 fraction 12.5 18.81 ± 0.90 32.22 ± 4.84 b
25 26.43 ± 9.70
50 84.44 ± 1.75
100 90.62 ± 0.33
S3 fraction 12.5 44.37 ± 4.50 21.17 ± 1.09 c
25 55.98 ± 3.57
50 82.61 ± 0.70
100 93.38 ± 0.23

Results are mean ± SD; *: 24 h of treatment; IC50 value: half maximal inhibitory concentration. Different letters (a–c) in the Table indicate significantly different at the level of p < 0.05 according to Scheffe’s test.