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. 2022 Feb 2;14(2):351. doi: 10.3390/pharmaceutics14020351

Table 2.

Cytotoxicity of bark essential oil and 6,7-dehydroroyleanone against Hep G2 cells.

Time
(h)
Specimen IC50
(μg/mL)
IC50
(µM)
24 Bark essential oil 54.31 ± 0.60 b -
6,7-Dehydroroyleanone 10.28 ± 0.18 d 32.74 ± 0.57 C
Etoposide * 76.89 ± 0.34 a 130.64 ± 0.58 A
48 Bark essential oil 30.27 ± 1.11 c -
6,7-Dehydroroyleanone 5.22 ± 0.09 e 16.62 ± 0.29 D
Etoposide * 29.68 ± 1.18 c 50.43 ± 2.01 B

Results are mean ± SD. *: Positive control. IC50 value: half maximal inhibitory concentration. Different letters (a–e; A–D) in the Table indicate significant difference at the level of p < 0.05 according to Scheffe’s test.