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. 2022 Feb 14;27(4):1279. doi: 10.3390/molecules27041279

Table 6.

Anti-inflammatory activities of enantiomers.

Assay Model Compds. IC50 (μM) Reference
BV-2/NO (+)-43a 26.4 [39]
(−)-43b 8.9 [39]
(+)-44a 5.9 [39]
(−)-44b 14.7 [39]
Quercetin a 17.0 [39]
RAW 264.7/NO (+)-82a 17.9 [54]
(−)-82b 5.6 [54]
(+)-83a 15.1 [54]
(−)-83b 4.3 [54]
RAW 264.7/NO (+)-221a 3.6 [124]
(−)-221b 22.8 [124]
(±)-221 14.7 [124]
Indomethacin a 42.2 [124]
BV-2/NO (+)-407a 6.9 [130]
(−)-407b 1.4 [130]
(±)-407 1.0 [130]
Minocyclinebe a 27.2 [130]

a positive controls.