Table 6.
Assay Model | Compds. | IC50 (μM) | Reference |
---|---|---|---|
BV-2/NO | (+)-43a | 26.4 | [39] |
(−)-43b | 8.9 | [39] | |
(+)-44a | 5.9 | [39] | |
(−)-44b | 14.7 | [39] | |
Quercetin a | 17.0 | [39] | |
RAW 264.7/NO | (+)-82a | 17.9 | [54] |
(−)-82b | 5.6 | [54] | |
(+)-83a | 15.1 | [54] | |
(−)-83b | 4.3 | [54] | |
RAW 264.7/NO | (+)-221a | 3.6 | [124] |
(−)-221b | 22.8 | [124] | |
(±)-221 | 14.7 | [124] | |
Indomethacin a | 42.2 | [124] | |
BV-2/NO | (+)-407a | 6.9 | [130] |
(−)-407b | 1.4 | [130] | |
(±)-407 | 1.0 | [130] | |
Minocyclinebe a | 27.2 | [130] |
a positive controls.