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. 2022 Feb 7;12(2):244. doi: 10.3390/life12020244

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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QFT-Plus indeterminate results and IFN-γ production in COVID-19 patients stratified according to the maximal oxygen supply needed during hospitalization. (a) Rates of determinate and indeterminate results at the QFT-Plus assay in COVID-19 patients stratified according to the maximal oxygen support needed during the entire hospitalization are represented. (b) The levels of IFN-γ in the Mitogen-Nil condition of the QFT-Plus assay in COVID-19 patients stratified according to the maximal oxygen support received during the entire hospitalization are represented. (c) As in (b), after removing COVID-19 patients with an indeterminate result of the QFT-Plus Assay. The histogram height represents the median value. Whiskers represent the interquartile range. QFT-Plus: QuantiFERON-TB Gold Plus; IFN-γ: interferon-γ; AA: ambient air; VMK: Venturi oxygen mask; NRM: Non-Rebreather Mask; NIV: non-invasive ventilation; OTI: orotracheal intubation for mechanical ventilation.