Table 1.
Baseline demographics of the methylene blue group compared to control group and propensity score-matched control group.
| Methylene Blue N = 60 |
Control N = 759 |
p-Value | Matched Control N = 60 |
p-Value | ||||
|---|---|---|---|---|---|---|---|---|
| Male sex | 51 | 85.0 | 580 | 76.4 | 0.082 | 44 | 73.3 | 0.177 |
| Age (y) | 62.3 | ±12.2 | 64.0 | ±13.6 | 0.351 | 62.0 | ±14.2 | 0.891 |
| BMI (kg/m2) | 27.5 | ±4.5 | 26.2 | ±4.3 | 0.024 | 26.7 | ±4.8 | 0.363 |
| ASA class | 0.062 | 0.414 | ||||||
| 1 | 0 | 0 | 1 | 0.1 | 0 | 0.0 | ||
| 2 | 0 | 0 | 1 | 0.1 | 0 | 0.0 | ||
| 3 | 12 | 20.0 | 293 | 38.6 | 10 | 16.7 | ||
| 4 | 42 | 70.0 | 419 | 55.2 | 39 | 65.0 | ||
| 5 | 6 | 10.0 | 45 | 5.9 | 11 | 18.3 | ||
| Procedure | <0.001 | 0.031 | ||||||
| Aorta | 16 | 26.7 | 107 | 14.1 | 7 | 11.7 | ||
| Valve | 21 | 35.0 | 302 | 39.8 | 20 | 33.3 | ||
| Bypass | 8 | 13.3 | 225 | 29.6 | 18 | 30.0 | ||
| Artificial heart | 5 | 8.3 | 69 | 9.1 | 9 | 15.0 | ||
| Combination | 4 | 6.7 | 22 | 2.9 | 0 | 0.0 | ||
| Other | 2 | 3.3 | 25 | 3.3 | 4 | 6.7 | ||
| Revision | 4 | 6.7 | 9 | 1.2 | 2 | 3.3 | ||
| Emergency | 13 | 21.7 | 151 | 19.9 | 0.738 | 16 | 26.7 | 0.335 |
Perioperative variables are shown regarding the use of MB versus standard therapy (matched control), indicating mean or percentage, respectively. This table also shows the results compared to the overall collective before matching. p-values indicate significance versus “methylene blue” group. BMI: Body mass index; ASA: American Society of Anesthesiologists.