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Differential cellular effects between UPCDC-30245 and CB-5083 or NMS-873 in HCT116 cells. (A) qRT-PCR analysis of CHOP, ATF3, p97 and p62 RNAs following treatment with DMSO, 5 μM of UPCDC-30245, 5 μM of CB-5083 or 5 μM of NMS-874 for 6 h. N = 3. ns, not significant; *, p < 0.05; **, p < 0.01; ***, p < 0.0005; ****, p < 0.0001; according to one-way ANOVA with multiple comparison tests. (B) The cellular viability curves for UPCDC-30245, CB-5083 and NMS-873. N = 4.
