Table 5.

Results of pharmacokinetics evaluation for the most promising kinase inhibitors.

Molecule	MW	#H-Bond Acceptors	#H-Bond donors	MR (Molar Refractivity)	TPSA	iLogP	BBB	Bioavailability	Drug Likeness
8	311.79	3	1	81.12	92.23	1.85	4.17	0.55	0.77
9a	415.51	5	2	114.49	130.29	3.11	3.09	0.55	0.90
9b	415.51	5	2	114.49	130.29	2.88	3.10	0.55	0.90
10a	362.45	5	1	101.34	104.7	2.45	3.60	0.55	1.06
11	360.49	2	2	103.76	110.69	3.46	4.29	0.55	0.52
12	312.39	2	2	91	101.18	2.63	4.01	0.55	0.57

# means (number).