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. 2022 Jan 19;14(2):227. doi: 10.3390/pharmaceutics14020227

Table 2.

Box–Behnken experimental runs of CTD-loaded GNE and their corresponding globule sizes.

Run Independent Variables Response
X1: Pumpkin Oil Concentration (%) X2: α-CD Concentration (%) X3: Homogenization Time (min) Y: Globule Size ± SD
(nm) *
E1 20.0 3.0 10.0 345 ± 12.4
E2 10.0 3.0 6.5 265 ± 9.7
E3 20.0 3.0 3.0 367 ± 12.9
E4 30.0 6.0 3.0 432 ± 11.8
E5 30.0 9.0 6.5 377 ± 10.9
E6 30.0 6.0 10.0 398 ± 13.8
E7 30.0 3.0 6.5 411 ± 12.9
E8 10.0 6.0 3.0 243 ± 8.5
E9 20.0 9.0 10.0 287 ± 9.1
E10 20.0 6.0 6.5 312 ± 11.2
E11 20.0 9.0 3.0 301 ± 9.9
E12 20.0 6.0 6.5 313 ± 10.2
E13 10.0 6.0 10.0 212 ± 7.3
E14 20.0 6.0 6.5 315 ± 9.7
E15 10.0 9.0 6.5 208 ± 6.5

* Results presented as average ± SD (n = 3).