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. 2022 Jan 29;14(2):322. doi: 10.3390/pharmaceutics14020322

Table 1.

Advantages and disadvantages of various nano-particles for cancer treatment.

Combination of PDT and Chemotherapy Type of Carriers Advantages Disadvantages
Without external carriers Photosensitizers as carriers
  1. Faster synthesis process

  2. Simple compound

  3. Cost-effective

  1. Possible toxicity

  2. Less-selectivity

  3. Fast elimination

Photosensitizer-drug materials
With external carriers Transition metal based nano-platforms
  1. Biocompatible

  2. Targeted drug carrier

  3. Selective

  4. Enhancing drug’s accumulation in the tumor site

  5. Tissue penetration

  6. Long time plasma half-life (stability)

  1. Complex compound

  2. Longer synthesis process

  3. More cost

  4. Complex elimination routes

Silica
Graphene
Liposomes
Dendrimers
Polymers
Metal–organic frameworks
Biological nanocarriers
Nano emulsions