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. 2022 Jan 29;14(2):322. doi: 10.3390/pharmaceutics14020322

Table 3.

Combination of photosensitizers and chemo-drugs with carriers.

Reference Photosensitizer Drug Carrier
[75] Photochlor Prodrug banoxantrone UiO-66-H/N3 (MOF)
[76] Merocyanine 540 Doxorubicin YbPO4:Er, Dy
[77] Mitoxantrone Mitoxantrone PEGylated Hollow gold nanoparticles
[78] Hematoporphyrin Docetaxel Gd-up conversion nanoparticles core/mesoporous silica shell
[79] Chlorin core star shaped block copolymer Camptothecin-11 Micelles
[80] Rose Bengal Platinum IV NaGdF4:Yb/Nd@NaGdF4:Yb/Er@NaGdF4
[81] Rose Bengal AB3, a histone deacetylase inhibitor NaYF4:Yb/Tm/Er
[82] Merocyanine 540 Doxorubicin NaYF4:Yb/Er
[83] Chlorin-e6 Camptothecin Up-conversion nanoparticles
[84] Pyropheophorbide Doxorubicin Up-conversion nanoparticles
[85] Chlorin-e6 c,c,t-[Diamine-dichlorodisuccinato-platinum(IV)] [Mg(1−x)Alx(OH)2][An−x/n]·zH2O
[86] Zinc(II) phthalocyanine Doxorubicin Mesoporous silica nanoparticle
[87] Chlorin-e6 Doxorubicin Polyethylene glycol
[88] Chlorin-e6 Doxorubicin Mesoporous silica nanoparticle
[89] Hematoporphyrin Doxorubicin Hollow Mesoporous Silica
[90] Aluminum chloride phthalocyanine Cisplatin Mesoporous silica nanoparticle
[91] PEGylated tetraphenylporphyrin zinc Doxorubicin Mesoporous silica nanoparticle
[92] Chlorin-e6 Doxorubicin Fe3O4@mSiO2(DOX)@ Human serum albumin
[93] Fullerene (C60) Doxorubicin Mesoporous hollow silica
[94] Chlorin-e6 Cisplatin Mesoporous silica nanoparticle
[95] 2-[1-Hexyloxyethyl]-2-devinyl pyropheophorbide Doxorubicin Liposome
[96] Chlorin-e6 Doxorubicin Microbubble-lipid mixture
[97] Indocyanine green-octadecylamine Doxorubicin Light sensitive liposome
[98] IR780 Tirapazamine Liposome
[99] Porphyrin Doxorubicin Dendritic poly(ethylene glycol) (PEG-G3-OH) copolymer
[100] 5,10,15,20-Tetraphenylchlorin Paclitaxel Red blood cells membrane-camouflaged nanoparticles
[101] Chlorin-e6 Doxorubicin Hybrid protein oxygen carriers
[102] Indocyanine green Doxorubicin Red blood cells containing oxyhemoglobin
[6] Chloroaluminum phthalocyanine Doxorubicin Nano emulsions
[103] CaFe2O4 Curcumin Polyvinyl alcohol
[104] Hypocrellin A 7-ethyl-10-hydroxycamptothecin Graphene oxide
[105] MnO2 Cis-Platine Graphene oxide
[106] 4-Hydroxy coumarin Camptothecin Graphene oxide
[107] Methylene blue Doxorubicin Graphene oxide
[108] Zinc(II) phthalocyanine Doxorubicin Methoxypolyethylene glycol (mPEG) and poly(β-benzyl-l-aspartate)
[109] Hematoporphyrin Doxorubicin Co-polymer containing arylboronic ester (BE)-modified with amphiphilic co-polymer (mPEG-PBAM).
[110] NIR dye-IR820 Docetaxel Methoxy-poly ethylene glycol-poly caprolactone
[111] Pyrolipid Oxaliplatin 1,2-distearoyl-sn-glycero-3-phosphocholine, cholesterol, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine polyethylene glycol 2000
[112] 4,4-difluoro-4-bora-3a,4a-diaza-sindacene Doxorubicin mPEG-polyaspartic acid-benzaldehyde
[113] Fluorogen photosensitizer Paclitaxel Poly(ethylene glycol)-b-poly(5-mthyl-5-propargyl-1,3-dioxan-2-one)
[114] Hematoporphyrin Doxorubicin PEGylated (cyclo-arginine-glycine-aspartic acid-d-phenylalanine-cysteine) peptide
[115] NIR fluorophore Paclitaxel Poly(ethylene glycol)-b-poly(5-mthyl-5-propargyl-1,3-dioxan-2-one)
[116] Hyaluronic Acid-chlorin-e6 Tirapazamine Self-assembling amphiphilic polyethylenimine-alkyl nitroimidazole
[117] Zn Docetaxel Co-polymers poly(ethylene oxide)-poly(ε-caprolactone)-poly(ethylene oxide)
[118] 5-aminolevulinic acid Doxorubicin Hydroxyethyl chitosan and aldehyde-functionalized hyaluronic acid
[119] Mesotetra(p-hydroxyphenyl) porphine Cis-platinum Mesotetra(p-hydroxyphenyl)-Pt-PEG (covalent-organic polymers)
[120] Chlorin-e6 Doxorubicin Hyaluronic acid-chlorin-e6
[121] C60 Doxorubicin C60–PEI–DOX
[122] Chlorin-e6 Doxorubicin (ε-caprolactone-co-lactide)-b-poly (ethylene glycol)-b-poly (ε-caprolactone-colactide)
[123] Merocyanine 540 Doxorubicin UCNP-loaded (NaYF4:Yb, Er) folate-conjugated polymeric (dextran)
[124] Pyropheophorbide-a gemcitabine Human serum albumin
[125] Zinc phthalocyanine Doxorubicin [methoxy-poly(ethylene glycol)-poly(2-(N,N-diethylamino)ethyl methacrylate)-poly(ε-caprolactone)]4-zinc β-tetra-(4-carboxyl benzyloxyl)phthalocyani
[126] Indocyanine green Doxorubicin Nano-scaled red blood cells
[127] Purpurin 18 Doxorubicin mPEG-Cyclodextrin-Polyhydroxybutyrate
[128] Gold nanoclusters Doxorubicin (ZIF-8) metal–organic framework
[129] protoporphyrin IX Doxorubicin (ZIF-8) metal–organic framework
[130] Chlorin-e6 Tirapazamine (polyethylene glycol)-Azo-benzene-poly (d, l-lactide-co-glycolide)
[131] Chlorin-e6 Gambogic acid Hyaluronic acid-nitroimidazole (HA-NI) as shells, MnO2 NPs functionalized poly (l-glutamic acid) derivatives (γ-PFGA) as cores
[132] Si photosensitizer Doxorubicin Mesoporous silica nanoparticle
[133] Chlorin-e6 Doxorubicin Polyoligo (ethylene glycol) methacrylate-block-poly(ε-caprolactone)-azobenzene-poly(ε-caprolactone)-block-poly oligo (ethylene glycol)
[134] Pyropheophorbide paclitaxel Poly [oligo (ethylene glycol) methyl ether methacrylate]
[135] Pheophorbide a Tirapazamine Self-assembled gelatin nanoparticles
[136] Chlorin-e6 Doxorubicin Poly(phosphorylcholine)
[137] Chlorin-e6 Oridonin Side-chain selenium-grafted polymers
[138] porphyrin Doxorubicin Tetra-β-cyclodextrin
[139] Chlorin-e6 Gemcitabine Polymeric micelles
[140] Chlorin-e6 Gemcitabine Multifunctional polymeric prodrug micelles
[141] Chlorin-e6 Paclitaxel Liposomes
[142] Chlorin-e6 Docetaxel Hyaluronic acid
[143] pyropheophorbide-a camptothecin mPEG with thioketal linker
[144] Chlorin-e6 Doxorubicin Block copolymers polystyrene-b-poly (acrylic acid) and oil-soluble
[145] Chlorin-e6 Perfluorohexanoate-modified cisplatin Poly(ethylene glycol)-lysine-block-poly(L-glutamate)-imidazole
[146] protoporphyrin IX Tegafur (prodrug of 5-fluorouracil) Heterodimers hydrogel
[147] zinc phthalocyanine Tirapazamine Hyaluronic acid
[148] Chlorin-e6 cisplatin Dual-effect liposome
[149] Porphyrin Paclitaxel Porphyrin-lipid shelled nano-emulsion
[150] 5-aminolevulinic acid to produce protoporphyrin IX Doxorubicin Nanogel