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. 2022 Feb 16;15(2):232. doi: 10.3390/ph15020232

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Photomicrographs of the parotid salivary gland of the studied groups. (a,b) The control and FEB groups, respectively, showed intact parotid parenchyma; serous acini (S) and striated ducts (D). Note the myoepithelial cells (↑). (c) The 5-FU group showed parenchymal changes; coalesced serous acini (S), pyknotic nuclei (↑↑), cellular infiltration (I), interrupted lining of striated ducts (arrowhead), retained secretion (*), and dilated congested blood vessels (↑). (d) The FEB + 5-FU group showed normal parotid structure; serous acini (S), striated ducts (D), and myoepithelial cells (arrowhead) except for mildly congested blood vessels (↑). (H&E ×400; 8 rats/group).