Table 1.

Impact of FEB on the physical parameters (ΔBW, parotid wt, and parotid index) of 5-FU-induced injury of the parotid salivary gland in rats.

Groups	ΔBW	Parotid wt (gm)	Parotid Index (%)
Control	18.38 ± 5.854	0.34 ± 0.09	10 ± 0.0
FEB	16.88 ± 4.35	0.32 ± 0.64	10 ± 0.0
5-FU	10.00 ± 7.42 ab	0.07 ± 0.02 ab	3.3 ± 0.39 ab
FEB + 5-FU	17.63 ± 5.29 c	0.29 ± 0.076 c	8.6 ± 0.84 c

Data are shown as their mean ± S.D (8 rats/group). ^a Significant difference from the control group, ^b significant difference from the FEB group, and ^c significant difference from the 5-FU group. (ΔBW: the difference between the terminal and initial body weights, 5-FU: 5-fluorouracil, and FEB: febuxostat.).