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. 2022 Feb 25;8(8):eabm3608. doi: 10.1126/sciadv.abm3608

Table 1. Elements of the SOPs followed by participants in the CDL RSC.

PCR, polymerase chain reaction.

Step Description
Preparation The preparation requires leadership and (if applicable) union buy-in and a clear assignment of responsibility.
Key decisions include who will administer the RATs (a health care professional, a trained professional,
or self-screening by the individual employees) and whether screening will be mandatory or voluntary.
Forms There are a variety of mandatory requirements and forms included in the process: the letter of agreement,
software licensing agreement, contact registration, team member registration, an invitation to the
CDL RSC community Slack workplace, new screening site, screen preorder, certificate of inventory, and
regular questionnaires on RATs used, cases detected, and operational challenges. These elements
are critical to ensure program fidelity and quality.
RATs and supplies Site leads need a process for calculating the number of screens that RATs required (number of
participants × 2 per week × number of weeks × 1.05 to allow for spoilage and training). There may also
be distinct types of equipment needed, including tables, chairs, timers, gloves, gowns, and biohazard
waste bags. The Canadian government provides RATs. RAT orders were tracked through a CDL RSC
form; CDL RSC coordinated directly with the supply chain managers in the federal and provincial
governments to support shipment fulfillment. For on-site screening programs, inventory control
requires daily checks and a full weekly inventory of all supplies.
Screening station layout and setup
where applicable
While there is some flexibility, there are several requirements for screening stations if they are on-site.
Waiting areas, traffic flow, and signage also need to be specified. Waiting areas, for example, require
floor markings to allow people to be safely distanced.
Communications and registration The program strongly encourages initial communication from the organization’s leadership. The goal is to
provide sufficient information so that employees can understand the program’s purpose, make an
informed decision about participation if voluntary, and give employees the opportunity to ask
questions. A standard consent form is required for all participants (see text S2).
Screening frequency and booking The program is anchored around regular screening, defined as at least twice every 7 days, as screening
more frequently is needed with a less sensitive test to reduce transmission. It is continually emphasized
that more frequent screening with a rapid turnaround time (i.e., isolating can happen right away) is as
effective as less frequent screening with a more sensitive test. The days that testing is available need to
be selected (e.g., Monday and Thursday) and communicated to employees.
Training The program provides written materials and video guides that provide the necessary training for self- or
supervised specimen collection. In addition, each screening kit comes with positive and negative control
swabs. These control swabs validate that the screening devices are working correctly and that the
administrator can perform and interpret the tests correctly.
Communicating results Employees are immediately informed of results or declare if self-screening. This is automatic if using an
application. It is recommended to collect another swab and repeat the RAT if inconclusive. To maintain
confidentiality, any in-person or phone conversations must be in a private area where others cannot
overhear. Furthermore, the participant should be able to ask questions. The employee should be told
the next steps, including collecting their belongings, going home to self-isolate, and arranging a
confirmatory diagnostic PCR test at a local assessment center. The organization also should begin their
plan for internal contact tracing and notification processes once the confirmatory PCR test result is
provided.
Data To keep track of whether individuals are screened at least twice every 7 days, it is necessary to keep some
identifying information for use only by the employer. A consent form and clear privacy policy are
therefore required. In addition, data collected are deidentified before being sent to the CDL RSC central
data infrastructure. This central data infrastructure is used to improve operations, prepare aggregated
reports with public health authorities, and conduct evaluations.