Fig 3. The effects of TNF-α inhibitor treatment on the sensitivity (LogEC50) and maximum responses (Emax) to vasodilatory substances in mesenteric arteries.
The sensitivity (LogEC50) to acetylcholine (A) and sodium nitroprusside (B) and the maximal relaxation response (Emax) to acetylcholine (C) and sodium nitroprusside (D) in the second branch of mesenteric arteries, in control, CIA and CIA+etanercept groups. Data expressed as means ± SEM. **p<0.001 versus control; †† p<0.001 versus CIA; using two-way ANOVA and Tukey post-hoc tests.