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AChE Inhibitory Activities of Analogs 1-12
| Compound | R | IC50s (nM) | Docking Score |
|---|---|---|---|
| Analog 1 |
|
793 | −18.4 |
| Analog 2 |
|
51 | −17.63 |
| Analog 3 |
|
334 | −17.24 |
| Analog 4 |
|
356 | −12.67 |
| Analog 5 |
|
2064 | −16.24 |
| Analog 6 |
|
1796 | −16.22 |
| Analog 7 |
|
364 | −13.42 |
| Analog 8 |
|
4318 | −14.01 |
| Analog 9 |
|
718 | −14.28 |
| Analog 10 |
|
414 | −13.59 |
| Analog 11 |
|
1116 | −16.11 |
| Analog 12 |
|
928 | −13.07 |
| Donepezil |
|
44 | −17.57 |
