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. 2022 Feb 22;37(1):792–816. doi: 10.1080/14756366.2022.2041627

Table 6.

The data of propidium iodide displacement assay towards compounds 5f, 7k and doneipezil.

Compound Propidium iodide displacement from AChE PAS (% inhibition)a
10 μM 50 μM
5f 25.7 ± 1.9 36.9 ± 3.5
7k 23.1 ± 1.2 34.3 ± 2.1
Donepezil 20.9 ± 2.7 33.4 ± 2.6

aPropidium iodide displacement assay was performed on AChE to test the ability of compounds 5f and 7k to displace propidium with reference to the donepezil at 10 and 50 μM. Data are presented as the mean ± SEM of three independent experiments.