Table 8.
Dyad-analysis/sweeping predictions in regions without binding sites reported in RegulonDB
Regulatory protein and genes shown to be regulated by it | Above threshold | Site coordinates and number of matches | Site sequence |
ArcA (12) | |||
aceB | - | i:-144;f:-85;m:8 | TTATCAAGTATTTTTAATTAAAATGGAAATTGTTTTTGATTTTGCATTTTAAATGAGTAG |
fadB | - | i:-96;f:-51;m:6 | ATTTCTTTAATCTTTTGTTTGCATATTTTTAACACAAAATACACAC |
fumA | + | i:-77;f:-56;m:14 | TATTGTTACTCGCTTTTAACAG |
fumC | - | i:-92;f:-53;m:10 | ATTTGTTATCAAATGGTAAATAATAAGTGAGCTAAAAGTT |
glpA | - | i:-248;f:-232;m:8 | TTATTTATGATTAACAG |
hyaA | - | i:-168;f:-150;m:12 | TACGCTTTATTAACAATAC |
lpdA | + | i:-232;f:-204;m:15 | TGTTTAAAAATTGTTAACAATTTTGTAAA |
sucA | - | i:-323;f:-300;m:5 | TGTTGTTGCAACGTAATGCGTAAA |
ArgR (11) | |||
argD | - | i:-63;f:-51;m:5 | TTTTTATGCATAT |
FNR (4) | |||
aspA | - | i:-156;f:-144;m:3 | TGATCTATTTCAC |
cyoA | + | i:-25;f:2;m:5 | GATCCCGTGGAATTGAGGTCGTTAAATG |
icdA | + | i:-306;f:-292;m:6 | ATTGAACAGGATCAC |
sdhC | - | i:-340;f:-326;m:2 | GATGATTAAAAATTA |
LexA (9) | |||
umuD | + | i:-57;f:11;m:24 | CTGCTGGCAAGAACAGACTACTGTATATAAAAACAGTATAACTTCAGGCAGATTATTAT |
GTTGTTTATC | |||
Lrp (1) | |||
livK | + | i:-277;f:-269;m:2 | CAGCATAAT |
sdaA | - | - | - |
serA | - | i:-146;f:-139;m:1 | CAGCATAT |
NarL (1) | |||
adhE | - | i:-215;f:-201;m:1 | TACCCAGAAGTGAGT |
caiF | - | - | - |
torC | + | i:-209;f:-195;m:2 | TACCCCTCCTGAGTG |
PurR (15) | |||
codB | + | i:-82;f:-64;m:16 | ACGAAAACGATTGCTTTTT |
prsA | + | i:-356;f:-344;m:21 | GAAAACGTTTTCG |
speA | - | i:-132;f:-119;m:6 | GAAACCGGTTGCGC |
Sequences and positions of binding sites predicted by dyad sweeping in genes with experimental evidence for co-regulation in RegulonDB, but with no binding site experimentally identified. Genes follow the alphabetic order of the regulatory proteins, with the name of the protein separating each group. The number in parentheses after the regulator is the value of the threshold - derived from requesting best overall performance. The site coordinates are 'i' for initial base, 'f' for final position relative to the start codon. The score is given as the maximum number of matching ('m') dyads within a ROM. The number of families used was the same for any method, but we only show families where the methods provided significant results.