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. 2022 Feb 18;36:5–9. doi: 10.1016/j.mmcr.2022.02.002

Table 1.

In vitro antifungal susceptibility test results and presence of mutation detected on CYP51A gene sequence of the nine isolates analyzed.

Isolate Days after first hospitalization Clinical specimen CLSI MIC (μg/mL)
CYP51A mutation
MCFG CPFG AMPH-B ITC VRC POS
LIF 3297 +12 Renal abscess 0.03 0.25 1 0.5 2 0.25 None
LIF 3309 +43 Renal abscess 0.015 0.12 2 0.5 2 0.25 None
LIF 3365 +114 Renal abscess 0.015 0.5 2 0.5 4 0.5 None
LIF 3492 +426 Prostate 0.015 0.25 2 0.5 2 0.25 None
LIF 3519 +427 Prostate 0.015 0.12 2 0.5 1 0.25 None
LIF 3495 +456 Prostate 0.015 0.25 1 0.5 1 0.25 None
LIF 3545 +489 Prostate 0.015 0.12 1 1 4 0.25 None
LIF 3546 +489 Renal capsule 0.015 0.12 2 2 >8 0.5 G448S
LIF 3608 +740 Pleural fluid 0.015 0.25 2 2 >8 1 G448S

MICs were determined using CLSI method M38-A2. MCFG, micafungin; CPFG, caspofungin; AMPH-B, amphotericin B; ITC, itraconazole; VRC, voriconazole; POS, posaconazole.