Table 1.
Clinical characteristics of all obese with NAFLD children
| Variable | rhGH group (n = 22) |
control group (n = 22) |
p value |
|---|---|---|---|
| Age (yr) | 12.04 ± 1.56 | 11.48 ± 1.78 | 0.272 |
| Prepuberty/Puberty, (n) | 16/6 | 15/7 | 0.741▲ |
| BMI SDS | 2.56 ± 0.65 | 2.75 ± 0.61 | 0.321 |
| CRP(mg/L) | 1.75 ± 1.06 | 2.06 ± 1.22 | 0.378 |
| ALT(U/L) | 24.50(14.75, 46.00) | 26.53(17.00, 60.25) | 0.452▲ |
| AST(U/L) | 25.50(22.00, 29.75) | 24.50(21.50, 34.25) | 0.953▲ |
| GGT(U/L) | 21.50(17.00, 30.00) | 28.00(21.00, 31.75) | 0.09▲ |
| TC(mmol/L) | 4.57 ± 0.60 | 4.46 ± 0.97 | 0.654 |
| HDL-C (mmol/L) | 1.24(1.07, 1.40) | 1.20(1.07, 1.37) | 0.717# |
| LDL-C (mmol/L) | 2.71 ± 0.45 | 2.68 ± 0.79 | 0.870 |
| TG(mmol/L) | 1.32(0.84, 1.87) | 1.21(0.92, 1.58) | 0.988# |
| UA(μmol/L) | 381.05 ± 112.52 | 370.90 ± 68.55 | 0.720 |
| Insulin(uIU/mL) | 24.13 ± 11.41 | 25.91 ± 13.01 | 0.631 |
| FBG(mmol/L) | 5.17 ± 0.39 | 5.18 ± 0.38 | 0.972 |
| HOMA-IR | 5.58 ± 2.79 | 5.99 ± 3.13 | 0.648 |
| WBISI | 3.22 ± 1.16 | 2.84 ± 1.52 | 0.349 |
| HbA1c (%) | 5.68 ± 0.24 | 5.66 ± 0.34 | 0.839 |
# p value reported for log transformed values, but values in the table represent as the median (interquartile range) ▲Mann–Whitney U test or chi square test
* p < 0.05
Abbreviations: BMI SDS body mass index standard deviation scores, CRP C reactive protein, ALT Alanine aminotransferase, AST Aspartate aminotransferase, GGT Gamma-glutamyl transferase, TC Total cholesterol, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol, TG Triglycerides, UA Uric acid, FBG Fasting blood glucose, HOMA-IR Homeostasis model assessment of IR, WBISI Whole body insulin sensitivity index, HbA1c Glycosylated haemoglobin