Table 1.

Association of MMP12 expression with clinical-pathological parameters of conventional RCCs without metastasis at the time of operation (n = 736)

		Nr of cases (736)	MMP12 expression			p-value
			Negative (549)	Weak (128)	Strong (59)
Gender						0.078
	Male	426	308	76	42
	Female	310	241	52	17
Status						< 0.001
	AWD	617	508	86	23
	PTR	119	41	42	36
Size						< 0.001
	< 4 cm	301	246	50	5
	4-7 cm	286	215	42	29
	> 7 cm	149	88	36	25
T Stadium						< 0.001
	pT1	574	463	85	26
	pT2	99	69	20	10
	pT3	63	17	23	23
Necrosis	No	658	517	103	39	< 0.001
	Yes	78	32	25	20
Grade						< 0.001
	G1	510	436	60	14
	G2	177	99	54	24
	G3	49	14	14	21
Stage						< 0.001
	I	570	461	84	25
	II	98	68	20	10
	III	68	20	24	24

AWD alive without disease, PTR postoperative tumour relapse