Table 3.
Analysis of innate and adaptive immune cells participating in the foreign body reaction to polypropylene meshes using regions of interest
| Marker (n = 7 PP meshes) | Cell density (cells/mm2) | % Marker+/Nuclei | % Marker+CD68−/Marker+ “conventional” |
|||
|---|---|---|---|---|---|---|
| Mean | SE | Mean | SE | Mean | SE | |
| Adaptive | ||||||
| CD3+ | 3,313.5 | 152.6 | 18.2 | 1.0 | 64.5 | 2.1 |
| CD4+ | 3,584.1 | 137.5 | 19.2 | 1.3 | 38.1 | 2.2 |
| CD8+ | 3,521.2 | 164.9 | 13.5 | 1.0 | 53.1 | 2.3 |
| CD20+ | 3,184.1 | 105.5 | 5.2 | 0.9 | 71.3 | 3.8 |
| FoxP3+ | 2,737.6 | 51.4 | 24.7 | 1.0 | 57.9 | 1.3 |
| Innate | ||||||
| CD11b+ | 3,065.7 | 102.5 | 20.2 | 1.5 | 52.0 | 2.1 |
| CD56+ | 3,108.3 | 80.0 | 9.8 | 1.1 | 45.2 | 2.6 |
| CD68+ | 3,206.1 | 51.6 | 25.0 | 0.5 | – | – |
The cell density is defined as the mean number of cells per mm2. Percentages of single-positive (Marker+) cells in relation to all cells and the proportions of “conventional” (Marker+CD68−) cells as function of all Marker+ cells. Hybrid cells with co-expression of CD68 were considered “disturbed”