Table 2.
Center for Study of Symptom Science, Metabolomics, and Multiple Chronic Conditions Common Data Elements
| Variable | Measurement |
|---|---|
| Demographic Factors | National Institutes for Nursing Research Common Data Elements |
| Age | BRICS forms (National Library of Medicine, 2016) |
| Race | |
| Ethnicity | Exact questions and responses shared for each pilot study |
| Gender | |
| Employment | |
| Education level | |
| Marital status | |
| Health insurance | |
| Household number | |
| Caregiver primary type | |
| Personal Health History | |
| Smoking status | Self-report (never, former, current) |
| Comorbidities | Charlson Comorbidity Index (Charlson et al., 1987) |
| Global Health | Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health Scale (National Institutes of Health, 2014) |
| Stress | Perceived Stress Scale SF (PSS–4; Cohen et al., 1983) |
| Stool | Bristol Stool Chart (Lewis & Heaton, 1997) |
| Medical Record Data | |
| Blood pressure | Average of three readings taken 5 min apart after sitting for 5 min or per medical record for visit with study’s biologic measure collection |
| Height | Standard stadiometer or per medical record for visit with study’s biologic measure collection |
| Weight | Calibrated scale, or per medical record for visit with study’s biologic measure collection |
| Hemoglobin | Point-of-care test or per medical record for recent visit |
| Self-Management Behaviors | |
| Dietary intake | Block-Bednar semiquantitative Food Frequency Questionnaire (modified to quantify probiotic intake; Block et al., 1990) |
| Medication intake | Self-report |
| Sleep | PROMIS Sleep Disturbance short form (National Institutes of Health, 2014) |
| Patient-Reported Symptoms and Outcomes | |
| Fatigue | Multidimensional Fatigue Inventory(MFI–20 ; Lin et al., 2009) PROMIS Short Form Fatigue 6a (National Institutes of Health, 2014) |
| Depression | Center for Epidemiological Studies Depression Scale (CES–D 10; Irwin et al., 1999; Radloff, 1977) PROMIS Short Form Depression 6a (National Institutes of Health, 2014) |
| Anxiety | State-Trait Anxiety Inventory (STAI; Spielberger, 1983) PROMIS Short Form Anxiety 6a (National Institutes of Health, 2014) |
| Pain | PROMIS Pain Intensity (National Institutes of Health, 2014) |
| Health-Related Quality of Life | NINR Common Data Elements BRICS Short Form 36 (National Library of Medicine, 2016) PROMIS Global Health Short Form 10 (National Institutes of Health, 2014) |
| Race-Related Stress | Index of Race-Related Stress ([IRRS], brief version; Utsey & Poterrotto, 1996) |
| Biologic Measures | |
| Metabolites | Blood samplea |
| Gut microbiome | Rectal swaba |
| Hemoglobin | Point-of-care test (if not collected per medical record) |
| Cytokines | Blood sample |
Note.
a
One of the supplement studies has a focus on oral health and is collecting saliva for microbiome and metabolomics analysis.