. Author manuscript; available in PMC: 2022 Aug 29.

Published in final edited form as: Pediatr Res. 2021 Aug 26;92(1):233–241. doi: 10.1038/s41390-021-01705-1

Table 2.

Unadjusted and adjusted Associations of in utero HIV/ART exposure with cord blood insulin and C-peptide

Model Outcome	HEU (median) (IQR)	HUU (median) (IQR)	Unadjusted Coefficient	p value	Adjusted Coefficient	p value

Insulin	14.6^a (10.9, 23.8)	12.6^a (8.8, 19.1)	0.248	0.05	0.305	0.03
C-peptide	1.04^b (0.80,1.56)	0.88^b (0.48, 1.15)	0.334	0.02	0.421	0.02

All models with outcomes log-transformed and adjusted for maternal age, maternal gestational diabetes, family history of diabetes, maternal pre-pregnancy body mass index, C-section delivery, infant sex, infant preterm birth, and infant birth weight z score

μIU/mL

ng/mL

ART=antiretroviral therapy; HEU=HIV/ART exposed uninfected; HUU=HIV/ARV unexposed uninfected; IQR=interquartile range