Figure 2.

(A) Diagnostic algorithm and (B) algorithm for treatment and follow-up of grade 1 DIILD in cancer patients. Grade 1 DIILD definition is adapted from the Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0 (27 November 2017).²⁸

BAL, bronchoalveolar lavage; CRP, C-reactive protein; CT, computed tomography; DIILD, drug-induced interstitial lung disease; DLCO, diffusing capacity of lung for carbon monoxide; ESR, erythrocyte sedimentation rate; HRCT, high-resolution computed tomography; LDH, lactate dehydrogenase; mTOR, mammalian target of rapamycin; SpO₂, oxygen saturation by pulse oximetry; TKIs, tyrosine kinase inhibitors.